Publications by authors named "B P Rosen"
A novel method for fast and high-resolution metabolic imaging, called ECcentric Circle ENcoding TRajectorIes for Compressed sensing (ECCENTRIC), has been developed at 7 Tesla MRI. ECCENTRIC is a non-Cartesian spatial-spectral encoding method designed to accelerate magnetic resonance spectroscopic imaging (MRSI) with high signal-to-noise at ultra-high field. The approach provides flexible and random sampling of the Fourier space without temporal interleaving to improve spatial response function and spectral quality.
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- * Thalamo-cortical spindles and Up states are crucial in coordinating co-ripples in the cortex and hippocampus during non-REM sleep.
- * The study suggests that instead of direct thalamic ripples, spindles and Up states are key in integrating information for memory consolidation during sleep.
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- Harmful algal blooms caused by cyanobacteria pose risks to ecosystems, the economy, and human health, with a focus on how nutrient introduction affects gene expression.
- Through mesocosm experiments, researchers discovered that adding nitrogen (specifically urea) resulted in longer-lasting blooms by enhancing key biological processes like photosynthesis and toxin production.
- The study highlights potential biomarkers for bloom longevity and sheds light on the mechanisms that allow cyanobacteria to thrive, which could aid in developing strategies to manage and mitigate these harmful blooms.
Compression neuropathy, such as carpal tunnel syndrome (CTS), results in changed afferent nerve signaling, which may result in changes in somatosensory brain areas. The purpose of this study was to assess cerebral changes following unilateral CTS and to assess short-term and long-term cerebral effects of guided plasticity treatment using ipsilateral cutaneous forearm deafferentation. Twenty-four patients with mild-to-moderate unilateral CTS were randomized to treatment with anesthetic cream (EMLA) or placebo.
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- The study investigates the spontaneous control of HIV/SIV viremia and its association with specific MHC class I allotypes, emphasizing the importance of CD8+ cytotoxic T lymphocytes (CTLs) for managing viral loads.
- Researchers aimed to understand the factors contributing to a phenotype known as elite controllers (ECs) by vaccinating rhesus macaques and analyzing immune responses after infection.
- Results showed that while vaccination did not prevent infection, it led to lower viral levels in vaccinated macaques, and 81% of them achieved elite control, highlighting differences in immune gene expression between vaccinated and unvaccinated groups.