Publications by authors named "B P Padhy"

Mutations of coding for polycystin-1 (PC1) account for most cases of autosomal-dominant polycystic kidney disease (ADPKD). The extracellular region of PC1 contains many evolutionarily conserved domains for ligand interactions. Among these are the leucine-rich repeats (LRRs) in the far N-terminus of PC1.

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Background: Medical management of adenomyosis is an emerging perspective in modern gynecology. Though levonorgestrel intrauterine system (LNG-IUS) and dienogest (DNG) effectively relieve symptoms in adenomyosis, neither has been approved for the same indication. Our study aims to compare the efficacy and safety of these progestins in treating adenomyosis.

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  • The study aimed to assess how effective the drug fezolinetant is in reducing vasomotor symptoms (VMS) like hot flashes in menopausal women and to identify any adverse effects.* -
  • After reviewing 330 articles, five studies were included in the meta-analysis, revealing that fezolinetant significantly decreased the frequency of VMS and improved sleep quality compared to a placebo.* -
  • Overall, the results suggest that fezolinetant is an effective treatment for alleviating moderate-to-severe VMS and related sleep disturbances in postmenopausal women.*
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  • Forensic medicine specialists in developing countries encounter numerous external challenges, alongside issues like poor infrastructure and limited human resources.
  • A study conducted at AIIMS, Bhubaneswar, revealed that approximately 20.5% of cases presented these challenges, mainly demands to reduce autopsy procedures or conduct them at inconvenient times.
  • The challenges were significantly influenced by factors such as the deceased's age, religion, socioeconomic status, and cause of death, leading to recommendations for minimizing invasive autopsies and adjusting procedures accordingly.
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