Publications by authors named "B P Molnar"
The progression of colorectal cancer is strongly influenced by environmental and genetic conditions. One of the key factors is tumor heterogeneity which is extensively studied by cfDNA and bulk sequencing methods; however, we lack knowledge regarding its effects at the single-cell level. Motivated by this, we aimed to employ an end-to-end single-cell sequencing workflow from tissue-derived sample isolation to exome sequencing.
View Article and Find Full Text PDFThe claustrum complex is viewed as fundamental for higher-order cognition; however, the circuit organization and function of its neuroanatomical subregions are not well understood. We demonstrated that some of the key roles of the CLA complex can be attributed to the connectivity and function of a small group of neurons in its ventral subregion, the endopiriform (EN). We identified a subpopulation of EN neurons by their projection to the ventral CA1 (EN.
View Article and Find Full Text PDFObjectives: To investigate the performance of a deep learning (DL) model for segmenting cone-beam computed tomography (CBCT) scans taken before and after mandibular horizontal guided bone regeneration (GBR) to evaluate hard tissue changes.
Materials And Methods: The proposed SegResNet-based DL model was trained on 70 CBCT scans. It was tested on 10 pairs of pre- and post-operative CBCT scans of patients who underwent mandibular horizontal GBR.
Objectives: To assess blood flow alterations after horizontal Guided Bone Regeneration (GBR) and to evaluate correlations between blood flow and hard tissue changes.
Method And Materials: Twelve mandibular surgical sites were involved in the current case series. GBR was carried out using a split-thickness flap design.
Article Synopsis
- The study focuses on developing a potential energy surface (PES) for the F- + SiH3I system, aiming to understand its gas-phase reactions using quasi-classical dynamics simulations.
- The PES is created using an automated process with Robosurfer, which handles various computational tasks and enhances the fitting set using a robust electronic structure calculation method, addressing potential issues in convergence and accuracy.
- Simulations reveal high reactivity in the system, with two primary product types (SN2 and proton abstraction) being observed, along with various other reactions, and the study also explores dynamics through trajectory animations.