Publications by authors named "B P L Wijnhoven"
Aim: The aim of this study was to assess Dutch surgical practice and outcomes for acute pilonidal abscess.
Method: Patients with pilonidal sinus disease (PSD) who underwent surgical treatment between 1 March 2020 and 1 March 2021 at 36 participating hospitals were included in a prospective observational cohort study. For the present study, only patients with an acute abscess were included for analysis.
Aim: Managing pilonidal sinus disease (PSD) remains challenging due to high recurrence rates and morbidity associated with treatment. The aim of this study was to evaluate the outcomes one year after surgical treatment for chronic PSD in the Netherlands.
Method: Patients with PSD who underwent surgical treatment between March 1, 2020, and March 1, 2021, at 36 participating hospitals were included in a prospective observational cohort study.
Background: The FLOT4 trial demonstrated superior survival of perioperative chemotherapy with 5-fluorouracil, oxaliplatin, and docetaxel (FLOT) compared to anthracycline triplets for resectable gastric cancer. These results were presented at the American Society of Clinical Oncology (ASCO) congress in June 2017 and published in April 2019. However, adoption of novel treatments in clinical practice often encounters delays.
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- - Oesophageal cancer patients achieving a clinical complete response (CR) after neoadjuvant chemoradiotherapy (nCRT) may benefit from active surveillance; however, identifying true CRs is difficult due to a 40% regrowth rate in these patients.
- - The study examined pre-treatment and post-treatment tissue samples to analyze the expression of several tumor markers (CEA, EpCAM, VEGF-α, EGFR, c-MET) through immunohistochemistry, aiming to find markers for potential near-infrared fluorescence imaging.
- - Results showed high expression of EpCAM in adenocarcinomas and EGFR in squamous cell carcinomas, while neoadjuvant therapy did not alter the