Transition medicine aims at the coordinated transfer of young patients with a chronic disease from paediatric to adult care. The present study reflects 20 years of experience in transitioning patients with congenital adrenal hyperplasia (CAH) in a single center setting. Our endocrine transition-clinic was established in 2002 and offers joint paediatric and adult consultations.
View Article and Find Full Text PDFBackground: Childhood primary brain tumors (CPBT) are the second largest group of childhood malignancies and associated with a high risk for endocrine late effects.
Objective: To assess endocrine late effects and their relevance for the development of osteopathologies in survivors.
Methods: This single center cross sectional study investigated data from 102 CPBT survivors with a mean age of 13.
Background: Genes, hormones and factors such as nutrition and psychosocial environment affect growth.
Objective: What is the significance of various psychosocial factors on growth?
Methods: Evaluation of results of a working meeting of paediatric endocrinologist with current literature research.
Results: Psychosocial deprivation in children can be associated with growth hormone deficiency (GHD) and short stature.
In ultra-rare bone diseases, information on growth during childhood is sparse. Juvenile Paget disease (JPD) is an ultra-rare disease, characterized by loss of function of osteoprotegerin (OPG). OPG inhibits osteoclast activation via the receptor activator of nuclear factor-κB (RANK) pathway.
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