Publications by authors named "B P Hauffa"

Transition medicine aims at the coordinated transfer of young patients with a chronic disease from paediatric to adult care. The present study reflects 20 years of experience in transitioning patients with congenital adrenal hyperplasia (CAH) in a single center setting. Our endocrine transition-clinic was established in 2002 and offers joint paediatric and adult consultations.

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Background: Childhood primary brain tumors (CPBT) are the second largest group of childhood malignancies and associated with a high risk for endocrine late effects.

Objective: To assess endocrine late effects and their relevance for the development of osteopathologies in survivors.

Methods: This single center cross sectional study investigated data from 102 CPBT survivors with a mean age of 13.

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Article Synopsis
  • Researchers are looking into different adrenal steroids (hormones) to see if they can help identify major depressive disorder (MDD) in teenagers.
  • A study with 261 depressed teens found that certain adrenal steroids were lower or higher compared to teens without depression.
  • The study suggests that a specific ratio of two steroids might help doctors figure out who needs special treatments for depression.
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Background: Genes, hormones and factors such as nutrition and psychosocial environment affect growth.

Objective: What is the significance of various psychosocial factors on growth?

Methods: Evaluation of results of a working meeting of paediatric endocrinologist with current literature research.

Results: Psychosocial deprivation in children can be associated with growth hormone deficiency (GHD) and short stature.

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In ultra-rare bone diseases, information on growth during childhood is sparse. Juvenile Paget disease (JPD) is an ultra-rare disease, characterized by loss of function of osteoprotegerin (OPG). OPG inhibits osteoclast activation via the receptor activator of nuclear factor-κB (RANK) pathway.

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