Publications by authors named "B P Fraser"

Objectives: To describe the associations between OA-related biochemical markers and knee symptoms in middle-aged adults followed up over 10-13 years.

Methods: Blood samples were collected during the Childhood Determinants of Adult Health (CDAH)-1 study (year: 2004-06) and 10-13 year follow-up at CDAH-3. Serum samples from baseline (n=156) and follow-up (n=167) were analyzed for three OA-related biomarkers [cartilage oligomeric matrix protein (COMP), matrix metalloproteinase (MMP)-3, and hyaluronan (HA)] using non-isotopic enzyme-linked immunosorbent assay (ELISA).

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Article Synopsis
  • Muscular strength, particularly measured by handgrip strength (HGS), is an important indicator of health and a predictor of age-related diseases, but no international benchmarks exist for HGS across different ages and sexes.
  • The study systematically analyzed data from over 2.4 million adults across 69 countries to establish sex- and age-specific norms for HGS, identifying a peak in strength between ages 30 and 39 before a gradual decline.
  • Findings revealed that while absolute and body size-normalized HGS improves slightly in early adulthood, a more significant drop occurs from middle to late adulthood, with males generally experiencing a faster decline than females.
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Background: Physical fitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health. However, inconsistencies in tests and protocols limit international monitoring and surveillance. The objective of the study was to seek international consensus on a proposed, evidence-informed, Youth Fitness International Test (YFIT) battery and protocols for health monitoring and surveillance in children and adolescents aged 6-18 years.

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Importance: Despite its relevance for pediatric blood pressure (BP) screening, the long-term predictive utility and natural progression of pediatric BP classification remain understudied.

Objective: To evaluate BP tracking from childhood to midadulthood using the American Academy of Pediatrics (AAP) thresholds and estimate transition probabilities among BP classifications over time considering multiple time points.

Design, Setting, And Participants: The analyses were performed in 2023 using data gathered from September 1980 to August 2018 within the longitudinal Cardiovascular Risk in Young Finns Study.

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During 2022-2023, the School Lunch Project (SLP) provided free nutritious cooked lunches 1-4 days per week to Kinder to Grade 10 students attending 30 schools in areas of high disadvantage in Tasmania, Australia. This analysis examined if the SLP was associated with student attendance. : Staff (teachers, support staff, and principals) from 12 schools completed an online survey and/or participated in focus groups/interviews.

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