Publications by authors named "B Ozdal"
Introduction: We aimed to demonstrate the sensitivity of frozen section for patients with adult granulosa cell tumor (AGCT) and analyze the clinico-pathological factors that may be associated with sensitivity.
Material Methods: This is a multicenter study including data of 10 Gynecological Oncology Departments. Frozen-section results of patients who had ovarian AGCT at the final pathology report were retrospectively analyzed.
Objective: The main feature of adult granulosa cell tumors (AGCT) is their capacity to secrete hormones, with nearly all of them capable of synthesizing oestradiol. The primary goal of this study is to identify synchronized endometrial pathologies, particularly endometrial cancer, in AGCT patients who had undergone a hysterectomy.
Materials And Methods: The study cohort comprised retrospectively of 316 AGCT patients from 10 tertiary gynecological oncology centers.
Article Synopsis
- The study investigates clinical, surgical, and pathological factors in patients with stage 1C adult granulosa cell tumors (AGCT), focusing on the role of adjuvant therapy in recurrence and survival rates.
- Out of 415 patients treated, 63 met the criteria for stage 1C AGCT, and comparisons were made between those receiving adjuvant chemotherapy and those who did not, measuring disease-free survival (DFS) outcomes.
- Findings showed that adjuvant chemotherapy did not significantly affect DFS or overall survival, indicating a need for further multicentric and randomized studies to validate these conclusions.
Article Synopsis
- The study focuses on analyzing Pap smear results that show atypical glandular cells, not otherwise specified (AGC-NOS), to identify potential cervical and endometrial lesions.
- A total of 254 women who had AGC-NOS results and subsequently underwent colposcopy were reviewed, revealing that around 27.6% had premalignant or malignant lesions, including 6.7% with actual malignancies.
- The findings suggest that careful evaluation of patients with AGC-NOS is crucial, with a recommendation for colposcopic examination and potential endometrial sampling to detect any underlying cancers.
OPEC study: An international multicenter study of ovarian preservation in endometrial cancers.
Int J Gynaecol Obstet
November 2022
Objective: To evaluate the feasibility and oncological safety of ovarian preservation in early stage endometrial adenocarcinoma (EC) patients aged 40 and below.
Methods: A total of 11 institutions from eight countries participated in the study. 169 of 5898 patients aged ≤40 years were eligible for the study.