STRUCTURAL CHANGES AND MORPHOMETRIC ANALYSIS OF CARDIOMYOCYTES IN RATS WITH ALLOXAN DIABETES.

The aim of this research was to study the ongoing structural changes in rat cardiomyocytes during alloxan diabetes and their morphometric analysis in dynamics, in particular 1 and 3 months after the start of the experiment. The experiment was performed on 20 Wistar rats of both sexes, weighing 200-250 g. Of these, 10 rats were controls, and 10 ones with experimental diabetes.

VITAMINS D AND E COMBINED EFFECT ON THE RAT MYOCARDIUM UNDER ALLOXAN-INDUCED DIABETES.

It is commonly known that in diabetes mellitus the risk of cardiovascular diseases and mortality increases. The purpose of this study was to determine the specific features of the morphological restructuring of the myocardium in the early stage of experimental diabetes and use the combined impact of powerful antioxidants (Vitamin C and Vitamin E) on the rat myocardium in conditions of alloxan-induced diabetes. The experimental animals were divided into three groups: 40 rats were the target, and 20 rats were the control.