Publications by authors named "B O James"
Background: Despite numerous government nutrition-specific and sensitive interventions, undernutrition (e.g., underweight) remains the major public health concern among under-five-year-old children in Ethiopia.
View Article and Find Full Text PDFAberrant protein glycosylation is a hallmark alteration of cancer and is highly associated with cancer progression. Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, but the -glycosylation of its glycoproteins has not been well characterized. In this work, we analyzed multiple freshly prepared PTC specimens along with paired normal tissue obtained from thyroidectomies.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates lymph node stromal cell cultures (LNSCs) from oral squamous cell carcinoma (OSCC) patients to understand tumor interactions for better treatment options.
- Primary cultures were developed from both metastatic and non-metastatic patient nodes, confirming their purity and revealing a variety of cell types.
- Transcriptomic and cytokine profiling showed different molecular alterations based on node status, with key insights into immune response and potential pathways for metastasis, highlighting the relevance of these models for future cancer research.
Introduction: Social activity is associated with better cognitive health in old age. To better translate epidemiological research for public health communication, we estimated relations of levels of social activity to average age at dementia onset.
Methods: In the Rush Memory and Aging Project (MAP), we followed 1923 dementia-free older adults and conducted annual clinical evaluations of dementia/mild cognitive impairment (MCI).