Publications by authors named "B O Grabarek"
Article Synopsis
- Hemodynamic instability and inappropriate postoperative pain perception (IPPP) pose significant challenges in managing patients undergoing elective open lumbar aortic aneurysm repair under general anesthesia, with inadequate opioid use risking adverse events.
- In a study involving 75 patients, three types of postoperative analgesia were tested: thoracic epidural anesthesia with ropivacaine, thoracic epidural with bupivacaine, and intravenous metamizole/tramadol, with the impact on pain levels and hemodynamic stability measured.
- Results showed that nearly half of the patients still experienced IPPP despite preventive measures, and while no acute pain was reported in the ropivacaine group, this was associated with noticeable hemodynamic instability; however
The purpose of this study is to evaluate clinical outcomes and early postoperative complications in patients undergoing Boston type I keratoprosthesis (BKPro) implantation, with a specific focus on the onset and nature of ocular surface disorders during the early postoperative period. This retrospective study included 77 eyes that underwent BKPro implantation between 2019 and March 2022. Patients were treated at the Saint Barbara Hospital, Trauma Centre, Sosnowiec, Poland, and District Railway Hospital, Katowice, Poland.
View Article and Find Full Text PDFThe purpose of this study was to evaluate the feasibility of using the expression profile of transforming growth factor beta (TGF-β-1-3) to assess the progression of L/S spine degenerative disease. The study group consisted of 113 lumbosacral (L/S) intervertebral disc (IVD) degenerative disease patients from whom IVDs were collected during a microdiscectomy, whereas the control group consisted of 81 participants from whom IVDs were collected during a forensic autopsy or organ harvesting. Hematoxylin and eosin staining was performed to exclude degenerative changes in the IVDs collected from the control group.
View Article and Find Full Text PDFEvaluating the Efficacy of Pre-Emptive Peribulbar Blocks with Different Local Anesthetics or Paracetamol Using the Adequacy of Anesthesia Guidance for Vitreoretinal Surgeries: A Preliminary Report.
Biomedicines
October 2024
Background/objectives: Precisely selected patients require vitreoretinal surgeries (VRS) performed under general anesthesia (GA) when intravenous rescue opioid analgesics (IROA) are administered intraoperatively, despite a risk of adverse events, to achieve hemodynamic stability and proper antinociception and avoid the possibility of intolerable postoperative pain perception (IPPP). Adequacy of anesthesia guidance (AoA) optimizes the titration of IROA. Preventive analgesia (PA) techniques and intravenous or preoperative peribulbar block (PBB) using different local anesthetics (LAs) are performed prior to GA to optimize IROA.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated changes in messenger RNA (mRNA) and protein levels in the tears of patients undergoing three types of laser vision correction: PRK, FS-LASIK, and SMILE, with samples collected before and after the procedures.
- - Results showed that PRK and FS-LASIK produced significantly higher biological responses, particularly with increased levels of interleukin-15 and vascular endothelial growth factor A, compared to SMILE, especially on the first day post-surgery.
- - By 180 days after the procedures, the levels of both mRNA and proteins in all groups had returned to levels similar to those before the surgeries, indicating a stabilization of expression.