Publications by authors named "B O Berg"
Study Design: N/A.
Objective: This study investigated the different ways of orbital floor reconstruction with special focus on reconstruction materials, imaging modalities (intra-/ post-operative), 3D printing and navigation.
Methods: The heads of all governmental-run or associated cranio-maxillofacial surgery units in Switzerland, Austria and Germany were asked in person or received an email link for an online survey with 12 questions.
Article Synopsis
- - Nitinol components in medical devices often face fatigue fractures due to small cracks starting at non-metallic inclusions before traditional crack growth occurs; understanding these cracks is essential for assessing device durability.
- - The study involved rotary bend fatigue tests on nitinol wire up to 2 billion cycles, measuring crack initiation from inclusions and calculating the stress intensity threshold.
- - The researchers propose that a smooth feature surrounding inclusions, observable under a scanning electron microscope, indicates ongoing crack growth, leading to a damage curve that helps predict the maximum allowable defect size for design life and loading conditions.
Purpose: Adherence to growth hormone treatment is known to affect growth outcomes. Both device preference and ease of use have been shown to affect treatment adherence. In this study, we assessed device preference and ease of use with two long-acting growth hormones, somapacitan (Sogroya, Novo Nordisk A/S) and somatrogon (Ngenla, Pfizer).
View Article and Find Full Text PDFSeveral empirical and theoretical studies suggest the presence of multiple enhancers per gene that collectively regulate gene expression, and that common sequence variation impacting on the activities of these enhancers is a major source of inter-individual gene expression variability. However, for the vast majority of genes, enhancers and the underlying regulatory variation remains unknown. Even for the genes with well-characterized enhancers, the nature of the combined effects from multiple enhancers and their variants, when known, on gene expression regulation remains unexplored.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to compare the long-term effects of arthroscopic partial meniscectomy (APM) versus exercise therapy on knee osteoarthritis (OA) progression and patient outcomes over a 10-year period.
- - It included 140 participants with degenerative meniscal tears, finding that the APM group had slightly more OA progression, with 23% developing radiographic OA compared to 20% in the exercise group.
- - Ultimately, both treatment methods showed no major differences in OA progression or strength, but both improved patient-reported pain and knee function.