Hepatocellular carcinoma screening in patients waiting for liver transplantation: a decision analytic model.

De novo hepatocellular carcinoma (HCC) may have a large impact on patients waiting for liver transplantation. The presence of HCC can lead to a status upgrade or removal from the waitlist. Our aim is to compare costs and outcomes of different liver cancer surveillance strategies.

Aplastic anemia complicating orthotopic liver transplantation.

The clinical characteristics and outcome of posttransplantation aplastic anemia (AA) were determined in 12 of 1,736 patients (0.007%) undergoing orthotopic liver transplantation (OLT) that were afflicted with AA. None of the affected patients had a history of hematologic disease.

Orthotopic liver transplantation for congenital biliary atresia. An 11-year, single-center experience.

Objective: The authors analyze a single center's 11-year experience with 190 orthotopic liver transplants for congenital biliary atresia.

Summary Background Data: Hepatic portoenterostomy generally is the initial treatment for children with congenital biliary atresia. Despite multiple modifications of the hepatic portoenterostomy, two thirds of treated patients still develop recurrent cholestasis, portal hypertension, cholangitis, and cirrhosis.

One thousand liver transplants. The lessons learned.

Objective: To evaluate the first 1000 liver transplants performed at UCLA Medical Center to determine factors responsible for improved results.

Summary Background Data: Liver transplant has evolved impressively since the first case was performed in 1963. The 1980s have highlighted this progress with the development of better organ preservation, standardization of operative procedure, improved immunosuppressive agents, and better understanding of patient selection.