Risk factors, complications, and outcomes of cystotomy in guinea pigs: 25 cases (2010-2023).

Objective: To describe the complications, surgical outcome, and prognosis associated with cystotomies in guinea pigs.

Methods: A retrospective review of medical records of guinea pigs undergoing cystotomy for uroliths or urethroliths between 2010 and 2023.

Results: 25 guinea pigs were included in the study.

Effect of Time and Sex on Post-Anterior Cruciate Ligament Reconstruction Psychological Patient-Reported Outcome Measure Scores.

Context: Low scores on psychological patient-reported outcomes measures, including the Anterior Cruciate Ligament-Return to Sport After Injury (ACL-RSI) and Injury-Psychological Readiness to Return to Sport (I-PRRS), after anterior cruciate ligament reconstruction (ACLR) have been associated with a maladaptive psychological response to injury and poor prognosis.

Objective: To assess the effect of time post-ACLR and sex on ACL-RSI and I-PRRS scores and generate normative reference curves.

Design: Case series.

Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial.

Various types of cellular injection have become a popular and costly treatment option for patients with knee osteoarthritis despite a paucity of literature establishing relative efficacy to each other or corticosteroid injections. Here we aimed to identify the safety and efficacy of cell injections from autologous bone marrow aspirate concentrate, autologous adipose stromal vascular fraction and allogeneic human umbilical cord tissue-derived mesenchymal stromal cells, in comparison to corticosteroid injection (CSI). The study was a phase 2/3, four-arm parallel, multicenter, single-blind, randomized, controlled clinical trial with 480 patients with a diagnosis of knee osteoarthritis (Kellgren-Lawrence II-IV).