Publications by authors named "B Niranjan"
Article Synopsis
- * The study explored the role of OCT1 in a CRPC xenograft model resistant to AR signaling inhibitors and chemotherapy, finding that OCT1 influences genes linked to cell migration and immune regulation, particularly highlighting the importance of the gene CTBP2.
- * Results suggest that targeting CTBP2 could provide a new therapeutic strategy for treating aggressive AR-positive CRPC by potentially enhancing immune response and tackling tumor progression.
There are diverse phenotypes of castration-resistant prostate cancer, including neuroendocrine disease, that vary in their sensitivity to drug treatment. The efficacy of BET and CBP/p300 inhibitors in prostate cancer is attributed, at least in part, to their ability to decrease androgen receptor (AR) signalling. However, the activity of BET and CBP/p300 inhibitors in prostate cancers that lack the AR is unclear.
View Article and Find Full Text PDFPurpose: A comparative evaluation of fluoride release and re-chargeability in conventional glass ionomer cement (GIC) (type II), Pediatric GIC (type IX), and Cention-N-an in vitro study at an interval of first, fourteenth, and twenty first days.
Methods: Three groups of test materials, each with twenty samples, were prepared. Measurements of the cumulative fluoride release [parts per million (ppm)] and re-release measured on the first, fourteenth, and twenty first days.
In recent years, health-care providers have seen more patients with difficult-to-treat wounds and burns. The biopolymer-based wound dressing protects the wounded area while assisting in the recovery of dermal and epithelial tissues throughout the healing process. The overall number of patients with chronic lesions has been expanding due to developing society, over weight, and cardiovascular illness.
View Article and Find Full Text PDFA Rare Gingival Lesion in Children: Fibroepithelial Hyperplasia.
Int J Clin Pediatr Dent
January 2022
Aim And Objective: This case report aims to describe the management of a case of rare gingival lesion in a young pediatric patient.
Background: An increase in the size of the gingival tissue is known as gingival hyperplasia. This can cause esthetic as well as functional problems, and interfere with normal functions like mastication and speech.