Publications by authors named "B Nicholson"
Objectives: This study aimed to explore the policy implementation of non-specific symptom pathways within the English National Health Service.
Methods: A multi-site ethnographic project was conducted in four hospitals that contained non-specific symptom pathways between November 2021 and February 2023. The research involved observation (44 h), interviews ( = 54), patient shadowing, and document review.
Endometriosis is a debilitating disease affecting 190 million women worldwide and the greatest single contributor to infertility. The most broadly accepted etiology is that uterine endometrial cells retrogradely enter the peritoneum during menses, implant and form invasive lesions in a process analogous to cancer metastasis. However, over 90% of women suffer retrograde menstruation, but only 10% develop endometriosis, and debate continues as to whether the underlying defect is endometrial or peritoneal.
View Article and Find Full Text PDFBackground: Presenting to primary care with fatigue is associated with a wide range of conditions, including cancer, although their relative likelihood is unknown.
Aim: To quantify associations between new-onset fatigue presentation and subsequent diagnosis of various diseases, including cancer.
Design And Setting: A cohort study of patients presenting in English primary care with new-onset fatigue during 2007-2017 (the fatigue group) compared with patients who presented without fatigue (the non-fatigue group), using Clinical Practice Research Datalink data linked to hospital episodes and national cancer registration data.
Prevalence and molecular epidemiology of methicillin-resistant Staphylococcus aureus in livestock farmers, livestock, and livestock products in southern Sri Lanka: A one health approach.
Infect Genet Evol
December 2024
Article Synopsis
- The study investigates MRSA prevalence and molecular epidemiology in livestock farmers, animals, and livestock products in southern Sri Lanka, using a One Health approach that connects human, animal, and environmental health.
- It found a low MRSA colonization prevalence in the region, with 24.0% in farms and 7.9% in farmers, while identifying two new MRSA clones in human and animal samples, but no livestock-associated MRSA (LA-MRSA) clones.
- The research underscores the need for ongoing MRSA surveillance to track transmission dynamics between humans and animals within the One Health framework.
Objective: To quantify the predictive value of unexpected weight loss for cancer according to patient's age, sex, smoking status, and concurrent clinical features (symptoms, signs, and abnormal blood test results).
Design: Diagnostic accuracy study (update).
Setting: Data from Clinical Practice Research Datalink electronic health records linked to the National Cancer Registration and Analysis Service in primary care, England.