Choosing the best apple: counselling leaflets and technologies of communication in the history of reproduction.

Historians have shown how the establishment of human genetic counselling in West Germany was characterised by several sociohistorical factors, in particular the impact of the legacies of Nazi biopolitics. These accounts have reconstructed continuities on an intellectual level which delayed a turn towards non-directive approaches, emphasising individual (emotional) well-being and voluntariness, and instead have prolonged a discourse that defined disability as an economic and social burden. However, while the distinct legacies of eugenics and racial hygienics are well researched, other factors that constituted counselling encounters, such as the ways of communicating reproduction and material objects' roles in transformations of concepts, actors and their relations, have not been examined in detail.

Determining Exception Context in Assembly Operations from Multimodal Data.

Robot assembly tasks can fail due to unpredictable errors and can only continue with the manual intervention of a human operator. Recently, we proposed an exception strategy learning framework based on statistical learning and context determination, which can successfully resolve such situations. This paper deals with context determination from multimodal data, which is the key component of our framework.

The environments of reproductive and birth defects research in the U.S. and West Germany (c. 1955-1975).

Most historiographies of the crossroads of environmental and reproductive health in 20th century start and end with the case of thalidomide. Despite its global scope, thalidomide today stands for sharp contrasts: in the numbers of victims, in institutional responses to the disaster, and also-more generally-in regulatory approaches to potential risks and national cultures of reproductive justice and disability rights. This paper takes a closer look at two countries that have been seen as emblematic of this divide in regulatory frameworks, despite similarities and interconnections in other areas, such as (pharma)industrial production, science, and robust feminist environmental health movements: the U.

The Duogynon controversy and ignorance production in post-thalidomide West Germany.

This article examines the West German controversy over Duogynon, a 'hormone pregnancy test' and the drug at the centre of the first major, international debate over iatrogenic birth defects in the post-thalidomide era. It recovers an asymmetrical power struggle over the uneven distribution of biomedical knowledge and ignorance (about teratogenic risk) that pitted parent-activists, whistleblowers and investigative journalists against industrialists, scientific experts and government officials. It sheds new light on the nexus of reproduction, disability, epidemiology and health activism in West Germany.

Sample displacement chromatography of monoclonal antibody charge variants and aggregates.

The rise of biosimilar monoclonal antibodies has renewed the interest in monoclonal antibody (mAb) charge variants composition and separation. The sample displacement chromatography (SDC) has the potential to overcome the low separation efficiency and productivity associated with bind-elute separation of mAb charge variants. SDC in combination with weak cation exchanging macroporous monolithic chromatographic column was successfully implemented for a separation of charge variants and aggregates of monoclonal IgG under overloading conditions.