Publications by authors named "B Neilan"
Article Synopsis
- Fungal endophytes significantly enhance the health and productivity of both native and cultivated plants, but research on their communities in eucalypt species remains limited.
- This study focused on the seasonal and spatial dynamics of fungal leaf endophytes in Eucalyptus crebra, finding that summer had significantly higher fungal diversity compared to autumn and spring.
- The results revealed different fungal compositions across seasons and canopy levels, with Ascomycota being the most prevalent phylum year-round, and highlighted the importance of monitoring endophytic fungi for the health of E. crebra and similar species.
Article Synopsis
- - Indolactam alkaloids are toxic compounds produced by certain actinobacteria and the cyanobacterium Moorena producens, known for causing skin issues like severe dermatitis and potential serious health risks from ingestion.
- - Notable types of these alkaloids include teleocidins, lyngbyatoxins, and others, which contain a common nine-membered lactam core made from l-tryptophanol and l-valine.
- - This chapter discusses the history and current understanding of indolactam alkaloids, including their isolation, structure, biosynthesis, biological effects, and methods of synthesis, covering research from their discovery in the 1960s up to 2024.
Lipidic drug delivery systems are responsive to the human microbiome.
J Colloid Interface Sci
January 2025
In vitro and in vivo tests for therapeutic agents are typically conducted in sterile environments, but many target areas for drug delivery are home to thousands of microbial species. Here, we examine the behaviour of lipidic nanomaterials after exposure to representative strains of four bacterial species found in the gastrointestinal tract and skin. Small angle X-ray scattering measurements show that the nanostructure of monoolein cubic and inverse hexagonal phases are transformed, respectively, into inverse hexagonal and inverse micellar cubic phases upon exposure to a strain of live Staphylococcus aureus often present on skin and mucosa.
View Article and Find Full Text PDFMicrocystins are hepatotoxic cyclic heptapeptides produced by some cyanobacterial species and usually contain the unusual β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid (Adda) at position-5. The full microcystin gene cluster from PCC 7806 has been expressed in . In an earlier study, the engineered strain was shown to produce MC-LR and [d-Asp]MC-LR, the main microcystins reported in cultures of PCC 7806.
View Article and Find Full Text PDFArticle Synopsis
- Bacterial antimicrobial resistance (AMR) is a growing global issue, particularly in under-researched environments like aquaculture ponds.
- A study in six Bangladeshi freshwater ponds revealed that urban ponds had greater bacterial diversity and higher levels of opportunistic pathogens compared to rural ones, with distinct microbial community structures observed.
- The presence of AMR genes, especially in urban ponds, poses risks for food safety and environmental sustainability, as aquaculture ponds are vital protein sources for local communities.