Publications by authors named "B Nebbad"
Article Synopsis
- A nationwide study in France assessed the effectiveness of fecal microbiota transplantation (FMT) for treating Clostridioides difficile infection (CDI) across 17 centers from 2018 to 2022.
- The study found an overall FMT success rate of 84.3% with very few severe adverse events, and it identified factors linked to CDI recurrence such as severe chronic kidney disease and inadequate bowel cleansing.
- Key factors for improving FMT success included proper manufacturing of the transplant, thorough bowel prep, and individualized delivery methods based on patient needs.
Objective: Tuberculosis (TB) disease has rarely been reported in patients with sickle cell disease, but it is associated with an increased risk of bacterial infections. In France, sickle cell disease is frequent in populations with the highest prevalence of TB disease. We aimed to highlight clinical aspects of TB disease in patients with sickle cell disease.
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- * A total of 53 patients with ICPTs were analyzed, with various assessment techniques used to examine colonization, including microbial cultures, scanning electron microscopy (SEM), and next-generation sequencing (NGS).
- * While no infections occurred, it was discovered that all ICPTs had bacterial colonization and mature biofilms were present on a significant number of them; antimicrobial treatment reduced microbial diversity but did not impact biofilm maturity.