Wetlands function as carbon sink: Evaluation of few floodplains of middle Assam, northeast India in the perspective of climate change.

Floodplain wetlands are biologically rich and productive ecosystems that can capture carbon (C) from the atmosphere through macrophytes and phytoplanktons and hold it in soil for a long time thus playing a critical role in mitigating climate change. The Assam state of India has about 1392 floodplain wetlands engulfing around 100,000 ha area in the Brahmaputra and Barak River basin. In the present study, five different wetlands in the middle Assam viz.

An overview of matrix metalloproteinase-12 in multiple disease conditions, potential selective inhibitors, and drug designing strategies.

Matrix metalloproteases (MMPs) are the proteolytic enzymes accountable for extracellular matrix (ECM) modification through their Zn-dependent catalytic activity. Among these, MMP-12 is one of the crucial MMPs that contributes to various disease states including different types of cancers and other major pathophysiological conditions including COPD, asthma, emphysema, skin diseases, arthritis, vascular diseases, and neurological disorders. The majority of the MMP-12 inhibitors should have three constitutional pharmacophoric features (i.

Derivatives of D(-)-glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-III: Synthesis, biological screening and in silico binding interaction analysis.

Tyrosine kinase inhibitors (TKIs) have markedly improved the overall survival rate of patients with chronic myeloid leukemia (CML), enabling them to achieve a normal life expectancy. However, toxicity, relapse, and drug resistance continue to pose major challenges in the clinical treatment of CML. The progression of leukemia is directly connected to higher expression levels and enzymatic actions of matrix metalloproteinase-2 (MMP-2).

Probing quantum geometry through optical conductivity and magnetic circular dichroism.

Probing ground-state quantum geometry and topology through optical responses is not only of fundamental interest, but it can also offer several practical advantages. Here, using first-principles calculations on thin films of the antiferromagnetic topological insulator MnBiTe, we demonstrate how the generalized optical weight arising from the absorptive part of the optical conductivity can be used to probe the ground-state quantum geometry and topology. We show that three-septuple-layer MnBiTe film exhibit an enhanced, almost-perfect magnetic circular dichroism for a narrow photon energy window in the infrared region.

Circulating microRNAs in Body Fluid: "Fingerprint" RNA Snippets Deeply Impact Reproductive Biology.

Circulating miRNAs (C-miRNAs) occuring in a cell-free form within body fluids and other extracellular environments have garnered attention in recent times. They offer deeper insight into various physiological and pathological processes which include reproductive health. This review delves into their diagnostic potential across a spectrum of reproductive disorders, including conditions affecting ovarian function, male infertility and post pregnancy issues.