Non-surgical Endodontic Management of a Permanent Maxillary Canine With Vertucci Type 3 Canal Configuration: A Case Report.

To achieve success in endodontic treatment, it is essential to have a thorough understanding of the root and canal morphology. While maxillary canines typically have a single root and canal, studies have reported variations in different populations. This case report details the non-surgical endodontic management of a maxillary canine (tooth no.

Treatment patterns in advanced/metastatic non-small-cell lung cancer in China: results from the CancerMPact survey 2021.

To report the treatment patterns of advanced/metastatic non-small-cell lung cancer (NSCLC) in China from a physician survey (CancerMPact).  A total of 206 Chinese physicians from 27 cities in urban mainland China reported on their treatment of NSCLC in September 2021. Platinum doublets received 70.

Enhanced Higher Harmonic Generation in Modified MAPbBrCl Single Crystal by Additive Engineering.

Mixed-halide perovskite materials (MHSCs) hold significant interest in photonics applications owing to their inherent advantages, including tunable bandgap properties, remarkable defect tolerance characteristics, and facile processability. These attributes position MHSCs as up-and-coming materials for various applications. However, the commercialization of these materials is severely affected by external factors, such as humidity and oxygen.

Aromatic Additives Boost the Terahertz Properties of Mixed Halide Perovskite Single Crystals.

Mixed halide perovskite (MHP) materials are promising candidates for photonic applications, owing to their tunable bandgap and pronounced optoelectronic properties. However, phase segregation in these materials severely impacts their scalability. The additive engineering (AE) strategy in the growth of most perovskite crystals (PSCs) has proven more effective.

p38MAPKα Stromal Reprogramming Sensitizes Metastatic Breast Cancer to Immunotherapy.

Unlabelled: Metastatic breast cancer is an intractable disease that responds poorly to immunotherapy. We show that p38MAPKα inhibition (p38i) limits tumor growth by reprogramming the metastatic tumor microenvironment in a CD4+ T cell-, IFNγ-, and macrophage-dependent manner. To identify targets that further increased p38i efficacy, we utilized a stromal labeling approach and single-cell RNA sequencing.