Publications by authors named "B Mrklic"
Objective: To assess the spasmolytic effect of drotaverine hydrochloride in colicky pain caused by renal and ureteric stones.
Patients And Methods: In a placebo-controlled, multicentre, multinational, randomized, double-blind study changes in the intensity of pain were recorded using a visual analogue scale (VAS), a four-grade (five points) pain intensity (PI) scale and a pain-relief scale. The primary endpoint was the evaluation of the antispasmodic effect of drotaverine during a 3-h study period, to confirm that drotaverine abolished or significantly decreased the intensity of pain in renal colic.