What Are the Barriers to Incorporating Nutrition Interventions Into Care of Older Adults With Femoral Fragility Fractures?

Femoral fragility fractures cause substantial morbidity and mortality in older adults. Mortality has generally been approximated between 10-20% in the first year after fracture and among those who do survive, another 20-60% require assistance with basic activities within 1-2 years following fracture. Malnutrition is common and perpetuates these poor outcomes.

'Tis Time 'Tis Time: The Importance of Operative Time, Thoroughness, and Shakespeare in Dair Procedures in Total Joint Arthroplasty.

Background: Prosthetic joint infections (PJIs), while rare, are a devasting complication of both total joint arthroplasty (TJA). With most patients undergoing surgical treatment for PJI, options vary between one-stage or two-stage (the gold standard) procedures. Debridement, antibiotics, and implant retention (DAIR) procedures are a common, less morbid alternative to two-stage revisions, but patients undergoing DAIR procedures more often experience reinfections.

Hypoxia offsets the decline in brachial artery flow-mediated dilation after acute inactivity.

Intermittent (IH), as opposed to continuous hypoxia (CH), is thought to have beneficial effects on cardiovascular function and health. In the present study, we examined the acute effects of IH and CH (∼80% pulse oxygen saturation via 10% oxygen tank) on peripheral vascular function. Brachial artery flow-mediated dilation (FMD) was used to assess vascular function in 12 young adults (23 ± 5 yr; 8 M/4 F) before and after 50 min of IH (5 cycles; 4-min normoxia/6-min hypoxia per cycle), CH (20-min normoxia followed by 30-min hypoxia), or time control (50-min normoxia) interventions.

Effect of cimetidine on oral digoxin absorption.

Cimetidine is a commonly prescribed histamine 2-receptor antagonist used in the treatment of gastric acid-related disorders. Cimetidine can interact with a number of drugs, including theophylline, benzodiazepine sedative hypnotics, warfarin, and antiarrhythmics. Problems may occur in patients receiving drugs with a narrow therapeutic index when combined with cimetidine.