Publications by authors named "B Mompean Morales"
Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and meta-regression of placebo controlled randomized controlled trials.
Curr Med Res Opin
December 2024
Article Synopsis
- GLP-1 receptor agonists (GLP-1RAs) show a modest decrease in low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) based on a review of clinical trials.
- The analysis found no significant impact on triglycerides, very low-density lipoprotein cholesterol (VLDL-C), or high-density lipoprotein cholesterol (HDL-C).
- Weight changes did not have a notable effect on LDL-C or TC levels among study participants.
Article Synopsis
- Male frogs use specific calls to attract mates and avoid competition, with their call characteristics influenced by their size and environment.
- The acoustic adaptation hypothesis suggests that frogs evolve their calls to improve their reach and clarity in their habitats.
- Research on Neotropical treefrogs revealed a significant relationship between body size and call frequency, but did not support the AAH claims linking calls to environmental factors, suggesting other influences like female choice may play a role.
Enzyme therapeutics are often compromised by poor accumulation within target tissues, necessitating high doses that can exacerbate off-target effects. We report an injectable supramolecular enzyme-peptide gel platform for prolonged local enzyme retention . The gel is based on CATCH(+/-) ( C o- A ssembling T ags based on CH arge-complementarity), cationic and anionic peptide pairs that form β-sheet fibrils upon mixing .
View Article and Find Full Text PDFIn chronic wound treatment, the debridement of devitalized tissue and the eradication of the biofilm must balance aggressiveness with care to protect regenerating tissues. In this study, urea, a potent chaotropic molecule, was modulated through the formation of a Natural Deep Eutectic Solvent (NADES) with betaine to develop a new debriding material (BU) suitable for application into injured dermal tissues. To evaluate BU's debriding capacity, along with its antibiofilm effect and biocompatibility, pre-clinical to clinical methods were employed.
View Article and Find Full Text PDFBackground: Given the pervasive issues of obesity and diabetes both in Puerto Rico and the broader United States, there is a compelling need to investigate the intricate interplay among BMI, pregestational, and gestational maternal diabetes, and their potential impact on the occurrence of congenital heart defects (CHD) during neonatal development.
Methods: Using the comprehensive System of Vigilance and Surveillance of Congenital Defects in Puerto Rico, we conducted a focused analysis on neonates diagnosed with CHD between 2016 and 2020. Our assessment encompassed a range of variables, including maternal age, gestational age, BMI, pregestational diabetes, gestational diabetes, hypertension, history of abortion, and presence of preeclampsia.