Publications by authors named "B Michelle Schweiger"

Article Synopsis
  • A 10-year-old boy experienced progressive muscle weakness, atrophy, and weight loss, along with symptoms like tachycardia, tremor, and learning issues.
  • Electromyography showed chronic myopathic changes, and lab tests indicated undetectable thyroid stimulating hormone, high thyroid peroxidase antibodies, and thyroid stimulating immunoglobulins.
  • After treatment with atenolol and methimazole, the boy's strength and cognitive abilities improved, emphasizing the need to consider reversible causes for neurologic symptoms in children.
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The unexpected emergence of oseltamivir-resistant A(H1N1) viruses in 2008 was facilitated in part by the establishment of permissive secondary neuraminidase (NA) substitutions that compensated for the fitness loss due to the NA-H275Y resistance substitution. These viruses were replaced in 2009 by oseltamivir-susceptible A(H1N1)pdm09 influenza viruses. Genetic analysis and screening of A(H1N1)pdm09 viruses circulating in Germany between 2009 and 2024 were conducted to identify any potentially synergistic or resistance-associated NA substitutions.

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Article Synopsis
  • Music therapy (MT) is being studied for its potential benefits on the brain development of very preterm infants (VPT) in neonatal intensive care units, with a focus on white matter microstructure.
  • A randomized controlled trial involving infants born before 32 weeks' gestation compared MT to standard care, with live MT sessions led by a trained therapist starting from the second postnatal week and assessed using advanced imaging techniques.
  • While initial analysis didn't show significant differences, further post hoc analysis indicated that MT might improve white matter integrity in certain brain areas, suggesting the need for larger studies to confirm these findings and understand their impact on long-term neurodevelopment.
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Respiratory viral infections (RVIs) are common reasons for healthcare consultations. The inpatient management of RVIs consumes significant resources. From 2009 to 2014, we assessed the costs of RVI management in 4776 hospitalized children aged 0-18 years participating in a quality improvement program, where all ILI patients underwent virologic testing at the National Reference Centre followed by detailed recording of their clinical course.

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BackgroundNon-pharmaceutical interventions (NPIs) during the COVID-19 pandemic affected respiratory syncytial virus (RSV) circulation worldwide.AimTo describe, for children aged < 5 years, the 2021 and 2022/23 RSV seasons in Germany.MethodsThrough data and 16,754 specimens from outpatient sentinel surveillance, we investigated RSV seasonality, circulating lineages, and affected children's age distributions in 2021 and 2022/23.

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