Publications by authors named "B Merron"
Double hit lymphoma: How do we define it and how do we treat it?
Best Pract Res Clin Haematol
September 2018
Double/triple hit lymphoma is recognised as a distinct entity within the heterogeneous group of high grade B-cell lymphomas, accounting for between 5 and 10% of cases of diffuse large B-cell lymphoma. Under the WHO 2016 it is now known as high-grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6. When treated with standard chemotherapy it has a poor outcome.
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- D-dimer tests, along with clinical pre-test probability scores, help assess the risk of venous thromboembolic events (VTE), but d-dimer levels can naturally rise with age.
- A recent review found that using an age-adjusted D-dimer for patients over 50 improves specificity without sacrificing sensitivity in low-risk VTE cases.
- This study analyzed patients who had ultrasound Doppler tests from 2011 to 2014, comparing the effectiveness of age-adjusted D-dimer levels against traditional cut-off values.