Publications by authors named "B McKusick"

Commercial milking of sheep is a new agricultural industry in the United States starting approximately 30 yr ago. The industry is still small, but it is growing. The majority of the sheep milk is used in the production of specialty cheeses.

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Objective: To evaluate the clinical efficacy of dexmedetomidine as a preanesthetic medication administered prior to anesthetic induction with ketamine or propofol and with or without isoflurane for maintenance of anesthesia.

Design: Randomized, blinded, controlled clinical trial.

Animals: 184 client-owned cats.

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Objective: To compare postoperative analgesia provided by a constant rate infusion (CRI) of dexmedetomidine (DMED) to that of a well-established positive control [morphine (MOR)] in critically ill dogs. The sedative, cardiorespiratory effects and clinical safety of a 24-hour DMED CRI were also evaluated.

Study Design: Prospective, randomised, blinded, positive-controlled parallel-group clinical study.

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Objective: To determine the effects of three rates of dexmedetomidine (DMED) constant rate infusion (CRI) on overall tissue perfusion, isoflurane (ISO) requirements, haemodynamics and quality of recovery in canine surgical patients.

Study Design: Prospective, randomized, blinded clinical study.

Animals: Client-owned dogs presented for soft tissue or orthopaedic surgery.

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Objective: To evaluate cardiovascular and respiratory effects and pharmacokinetics of a 24-hour intravenous constant rate infusion (CRI) of dexmedetomidine (DMED) during and after propofol (PRO) or isoflurane (ISO) anaesthesia in dogs.

Study Design: Prospective, randomized, cross-over study.

Animals: Ten healthy adult Beagles.

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