Publications by authors named "B Marinescu"

Radiation injuries, particularly those resulting from therapeutic or accidental exposure, present complex challenges for medical management. These injuries can manifest localized skin damage or extend to deeper tissues, presenting as various clinical entities that require treatment strategies, ranging from conservative management to complex surgical interventions. Radiation treatment constitutes a fundamental component of neoplastic management, with nearly two out of three oncological instances undergoing it as an element of their therapeutic strategy.

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Article Synopsis
  • - G protein-coupled receptor G2A is considered a promising target for therapies related to neuropathic pain, acute myeloid leukemia, and inflammation, but effective G2A agonists are still underdeveloped.
  • - Researchers discovered a new potent and selective G2A agonist scaffold, specifically T-10418, which showed higher potency compared to existing ligands like 9-HODE.
  • - T-10418 has a favorable profile, including excellent solubility and metabolic stability, making it a valuable tool for studying G2A activation effects.
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Head and neck defects after tumor resection can be difficult to reconstruct using autogenous tissue without utilizing a free flap. Osteocutaneous fibula free flap is now considered the gold standard used for mandibular reconstruction after resections due to malignancy. We present the case of a 49-year old female known with an ectopic mucoepidermoid carcinoma involving the mandibula from one ramus to another.

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The presence of hyaline cartilage has been previously documented in heart tissue of different vertebrates, ranging from birds to superior mammals. However, there is scarce published data regarding the appearance of focal deposits of hyaline-like cartilage within the hearts of laboratory rats. Few mechanisms that could trigger the appearance of this type of cartilage in heart were hypothesized (e.

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Peripheral nerve injuries (PNIs) can be most disabling, resulting in the loss of sensitivity, motor function and autonomic control in the involved anatomical segment. Although injured peripheral nerves are capable of regeneration, sub-optimal recovery of function is seen even with the best reconstruction. Distal axonal degeneration is an unavoidable consequence of PNI.

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