Publications by authors named "B Maliakkal"

Introduction The use of glucagon-like peptide-1 receptor agonists (GLP-1 RA) has gained acceptance in managing diabetic and non-diabetic patients, thanks to its benefits in treating obesity and improving cardiovascular outcomes. The potential ability of GLP-1 RA to cause retained gastric contents (RGC) which can lead to aspiration has led to the recommendation to withhold GLP-1 RA for at least one week prior to elective surgeries and procedures, including upper endoscopies and colonoscopies. However, many co-medications and conditions associated can contribute to delayed gastric emptying (DGE) and these need to be controlled to establish a clear association and incidence, which has been largely missing in most studies and reports.

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Article Synopsis
  • A study was conducted to improve non-invasive detection methods for colorectal neoplasia, especially adenomas, by comparing a fecal test using a monoclonal antibody (Adnab-9) to the standard guaiac-based fecal occult blood test (gFOBT).
  • The results showed that the p87 immunohistochemistry test was significantly more sensitive than gFOBT for detecting adenomas and advanced adenomas, with odds ratios indicating its superior detection capabilities.
  • Additionally, findings suggested that urine tests for specific neoantigens may also provide useful information, particularly for advanced adenomas, making p87 fecal testing a promising tool for enhancing colonoscopy screening efforts.
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A duodenal perforation is a serious complication that can occur during endoscopic retrograde cholangiopancreatography (ERCP), particularly if it is associated with therapeutic endoscopic sphincterotomy. Therefore, it is crucial to identify and manage it early to achieve the best possible outcome. Conservative management may be attempted; however, surgical intervention is required if signs of sepsis or peritonitis are present.

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(Guduchi/Giloy) is a relatively common herbal supplement whose use has recently become prominent in Southeast Asia. It was promoted to the public in India as an immunity booster, especially against the novel COVID-19. There have been reports, mostly from India, of an association between Guduchi/Giloy and liver injury.

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Colovesical fistula is one of the known complications of acute diverticulitis. However, it is uncommon for a patient to present with a colovesical fistula without prior episodes of diverticulitis. In this case, we report a patient with acute diverticulitis presenting with a colovesical fistula with no antecedent history of any medical condition.

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