Publications by authors named "B Mahendran"

Background:  Headaches affect people's social, intellectual, and personal lives and are quite common worldwide, especially among young adults. Primary headaches that cause significant impairment, such as tension-type headaches (TTH) and migraines, frequently start in adolescence and early adulthood. Research on the incidence and consequences of headache problems among young people in India is scarce, especially when it comes to a variety of academic fields.

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  • The study found that 34.6% of adults aged 40 and older in rural South India have knee osteoarthritis (OA), highlighting a significant public health issue.
  • Significant risk factors for developing OA included diabetes, obesity, and hypertension, particularly in women.
  • The study also revealed that OA patients experience high levels of pain during activities like standing up from a chair and climbing stairs, with an average WOMAC score indicating considerable functional impairment.
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  • Transplantation is a radical therapy that involves removing the liver and its associated structures, then replacing them with a donor liver (allograft).
  • Recent studies show liver transplantation is possible for patients with unresectable colorectal liver metastases (CRLM) and can lead to acceptable outcomes in carefully selected individuals.
  • There are ethical concerns about this approach, such as the risk of disease recurrence in patients who are immunosuppressed and the limited availability of donor livers, which may affect access for those with other liver conditions.
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  • - The study investigates the relationship between donor time to death (TTD) and outcomes in liver transplantation from donors after circulatory death (DCD), analyzing data from the UK Transplant Registry for recipients between 2006 and 2021.
  • - Results indicated that a TTD of 14 minutes or less significantly increased the risk of graft loss, while longer TTD did not affect outcomes; additionally, prolonged surgery time was associated with graft loss but not the duration of functional warm ischemia.
  • - The findings suggest that allowing longer stand down periods before organ procurement may enhance the use of donor livers without compromising transplant success rates.
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