Publications by authors named "B M Weissman"

Endometrial cancer [EC] is the fourth most common cancer in women in the United States. Stark racial disparities are present in EC outcomes in which Black women have significantly higher EC-related mortality than White women. The social and biologic factors that contribute to these disparities are complex, and may include racial differences in epigenetic landscapes.

View Article and Find Full Text PDF
Article Synopsis
  • 2C is an illicit drug combining effects of ketamine, MDMA, methamphetamine, cocaine, and opioids, known for hallucinogenic and stimulant properties.
  • A case study highlights a 22-year-old woman with bipolar I disorder who experienced severe symptoms after using 2C, including visual hallucinations and increased heart rate.
  • The report emphasizes the necessity for healthcare providers to identify 2C intoxication signs and calls for more research and public health efforts due to the drug's growing recreational use.*
View Article and Find Full Text PDF

Purpose: To test the impact of professional management of soft contact lens wear on symptoms and ocular complications.

Methods: Subjective symptoms and ocular complications of soft CL users who did not seek professional follow-up care (self-managed, SM), were compared to users who were prescribed CLs and their care professionally managed in optometry practices (PM), and to a control group of non-CL wearers. Habitual visual acuity, subjective dry-eye symptoms, and corneal abnormalities were assessed in all participants.

View Article and Find Full Text PDF

Purpose: Large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine malignancy that, like small cell lung cancer (SCLC), is associated with the absence of druggable oncogenic drivers and dismal prognosis. In contrast to SCLC, however, there is little evidence to guide optimal treatment strategies, which are often adapted from SCLC and non-small cell lung cancer approaches.

Experimental Design: To better define the biology of LCNEC, we analyzed cell line and patient genomic data and performed IHC and single-cell RNA sequencing of core needle biopsies from patients with LCNEC and preclinical models.

View Article and Find Full Text PDF

Background/importance: Chronic pain affects many people globally, requiring alternative management strategies. Psilocybin is gaining attention for its potential in chronic pain management despite being classified as Schedule I.

Objective: This systematic review critically evaluates the evidence for psilocybin, a Schedule I substance, in the treatment of chronic pain.

View Article and Find Full Text PDF