Publications by authors named "B M Refaat"
Background: Edible fruits and resins provide various benefits to mankind including potential medicinal applications. This study aimed to determine the cytotoxicity, selectivity, and clonogenicity of fruits and exudates of certain Saudi medicinal plants ( (BEP-09), (L.) Miller (BEP-10), Roxb.
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- The study investigates the combined effects of sodium-glucose cotransporter-2 inhibitors (SGLT2i) and vitamin D (VD) on metabolic dysfunction-associated steatohepatitis (MASH) in type 2 diabetic mice, filling a gap in previous research.
- Diabetic mice were subjected to a high-fructose/high-fat diet and then treated with either SGLT2i, VD, or both, revealing that while SGLT2i alone was effective, the combination treatment offered superior protection.
- Results showed significant improvements in metabolic parameters, liver health, and reductions in inflammation and oxidative stress markers, indicating that the combined therapy enhances hepatic protection against diabetes-induced MASH.
Fungi play a significant role in the deterioration of various types of monuments. Therefore, the protection of ancient monuments from fungal attacks is an important goal that must attract the attention of researchers worldwide. A total of 69 fungal isolates were recovered from 22 deteriorated objects compromising paper, textiles, wood, and stone in the National Museum of Egyptian Civilization (NMEC) storeroom, Cairo, Egypt.
View Article and Find Full Text PDFIntroduction: Blood donation is vital for healthcare; however, transfusion-transmitted infections (TTIs) pose a serious risk. This study investigated the seroprevalence of TTIs among Saudi blood donors.
Methodology: This retrospective study included male blood donors aged ≥ 18 years who donated blood at Al-Noor Specialist Hospital in Makkah from January 2017 to December 2022.
Background: Metastatic secondary ocular tumors spread from systemic malignancies, including breast cancer. This study aimed to evaluate the cytotoxicity of extracts from 5 medicinal plants native to Saudi Arabia.
Methods: For preliminary activity screening, cytotoxicity using the MTT assay and selectivity index determinations were made for medicinal plant extracts against various cancer cell-lines.