Possibilities of chromoesophagoscopy for diagnosis of Barrett's esophagus.

When the distal esophagus is covered with columnar gastric mucosa up to 2 cm from the esophagogastric junction it is considered normal. If the distal esophagus is covered with columnar epithelium more than 2 cm from the esophagogastric junction, it is called Barrett's esophagus. We have developed a new chromoesophagoscopic method to improve diagnostic testing for Barrett's esophagus.

[Morphofunctional evaluation of the results of reconstructive operations of gastroenteroanastomosis in peptic ulcer].

The mucosa of the gastric stump, abducting and adducting loops of small intestine in patients with peptic ulcers of gastrointestinal anastomosis has been examined with scanning, transmission electron and light microscopy, morphometry, and the study of secretion at various periods after reconstructive surgery combined with vagotomy. An increase of the number of chief and parietal cells in the gastric stump fundal glands, increase of the thickness of the mucosa due to the deepening of the crypts of the adducting and abducting loops of the small intestine, and alteration of the mucosal microrelief of the gastric stump and small intestine are noted in peptic ulcers of gastrointestinal anastomosis especially near the site of anastomosis. This is accompanied by an increase of mucosal secretory activity.

[Effect of truncal vagotomy on the state of pyloric muciferous cells].

The pyloric glands and muciferous superficial cells of the pyloric mucosal membrane have been studied in 62 patients with complicated forms of duodenal ulcer--preoperatively, 2--4 weeks, 6--12 months following truncal vagotomy with drainaged stomach. The light transmission and scanning electron microscopy and stereometry, were used as well as the determination of mucosal production and intragastric pHmetry. It is shown that vagotomy leads to a decrease of inflammatory changes without an essential influence on the pyloric gland size.