Publications by authors named "B M McLaughlin"
Background: The limited understanding of factors influencing the disease progression of oral lichen planus (OLP) poses challenges in delivering effective and personalised treatment for this condition, known to increase the risk of oral cancer and adversely impact patient quality of life.
Objective: This study aimed to systematically identify clinical predictors of disease severity in OLP patients.
Methods: This cross-sectional and single-site prospective study was conducted between December 2021 and February 2024 in the Departments of Oral Medicine and Oral & Maxillofacial Surgery, Aberdeen Royal Infirmary.
Climate change is projected to cause extensive plant range shifts, and, in many cases such shifts already are underway. Most long-term studies of range shifts measure emergent changes in species distributions but not the underlying demographic patterns that shape them. To better understand species' elevational range shifts and their underlying demographic processes, we use the powerful approach of rephotography, comparing historical (1978-1982) and modern (2015-2016) photographs taken along a 1000-m elevational gradient in the Colorado Desert of Southern California.
View Article and Find Full Text PDFMcLaughlin, Gotlieb, and Mills introduced the concept of problematic news consumption (PNC) in their 2023 study, finding that those classified as having severely problematic news consumption (16.5% of the sample) exhibited significantly greater levels of mental and physical ill-being. These results were the product of a single cross-sectional survey, however.
View Article and Find Full Text PDFArticle Synopsis
- People who inject drugs often face hospital admissions due to substance use complications and frequently continue using nonprescribed drugs while hospitalized, which can lead to increased health risks.
- Punitive and abstinence-based approaches to manage drug use in hospitals disproportionately harm vulnerable communities, especially Indigenous peoples affected by systemic discrimination and colonial legacies.
- To improve care, Canadian hospitals should adopt harm reduction strategies, provide cultural safety training for clinicians, and collaborate with academic institutions to support the recruitment and retention of Indigenous healthcare professionals.
Background:: Prospective data of sequencing PD-L1 inhibition after PD-1 inhibition is limited in non-small cell lung cancer (NSCLC). We report a phase II clinical trial of atezolizumab following PD-1 directed therapy (NCT03014648).
Methods:: Previously treated advanced NSCLC patients were enrolled in cohorts based on response to prior nivolumab or pembrolizumab therapy; progressive disease (Cohort 1); stable disease (Cohort 2), or partial or complete response (Cohort 3).