Publications by authors named "B M MARCHESINI"
Article Synopsis
- Regular physical activity helps prevent obesity by increasing energy expenditure, where the PPARGC1A gene plays a key role in producing the hormone irisin, which promotes fat burning.
- This study examined genetic variants in genes related to fat metabolism among 210 individuals with severe obesity and 191 normal-weight subjects to assess their impact on obesity-related traits.
- The results identified specific genetic variants linked to severe obesity and found a novel mutation in the FNDC5 gene, indicating that these genetic factors contribute significantly to obesity susceptibility.
Article Synopsis
- Obesity is a significant global health issue influenced by genetics and environment, with the FTO gene identified as a key genetic factor.
- This study analyzed FTO gene variations (specifically rs9939609 and rs17817449) in 169 normal-weight and 123 extremely obese subjects to assess their impact on obesity and related health metrics.
- Results indicated a strong link between FTO variants and extreme obesity, with specific haplotypes increasing obesity risk, and certain polymorphisms affecting BMI and triglyceride levels, though no effect on the onset age of obesity was observed.
Objectives: to study mortality rates among workers in companies manufacturing thermoplastic and rubber articles (excluding tyres).
Design: cohort study.
Setting And Participants: the cohort includes 4,543 workers employed up to 2000 in 131 companies in the Province of Bologna (Emilia-Romagna Region, Northern Italy) exposed to emissions from hot processing of plastics (3,937) and rubber (606).
[Biological monitoring of the PAH exposure in the hardening of metals].
G Ital Med Lav Ergon
April 2013
The hardening of metals involves the immersion of hot components in mineral oil with production of aerosols containing PAHs, to wich workers can be exposed. The determination of airborne PAHs and urinary 1-hydroxypyrene (1-OHPy) was performed for a group of workers and the latter resulted within the reference values. However, the average 1-OHPy concentration on metal workers (0.
View Article and Find Full Text PDFRelatively little is known about occupational and other risk factors for renal-cell carcinoma (RCC). Associations between RCC and occupations, exposures and other factors were investigated in a hospital-based case-control study in Bologna (central-northern Italy). Between 1986 and 1994, 324 histologically confirmed RCC cases were diagnosed at Policlinico S.
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