Publications by authors named "B M Fagan"

With the Food and Drug Administration's approval of the first over-the-counter naloxone nasal spray in 2023, it was expected that access to naloxone nasal spray would increase and that its cost would be reduced. However, the writers of this commentary found varying insurance coverage of naloxone during purchase attempts at local pharmacies. Failure to cover naloxone can reduce access and increase risk of overdose death.

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Article Synopsis
  • Humans have changed ecosystems and biodiversity around the world for a long time, but we don’t fully understand how these changes have happened over time.
  • Researchers studied a lot of pollen samples to see how plant communities have changed for thousands of years, finding that differences in plant types and numbers have varied across the globe.
  • In some areas, as humans impacted the land, biodiversity increased, while in other places, it decreased, showing that humans have both helped and harmed plant diversity over the last 8,000 years.
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Gut microbiomes of mammals carry a complex symbiotic assemblage of microorganisms. Feeding newborn infants milk from the mammary gland allows vertical transmission of the parental milk microbiome to the offspring's gut microbiome. This has benefits, but also has hazards for the host population.

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Background: Neutrophil extracellular traps (NETs) occur when neutrophil chromatin is decondensed and extruded into the extracellular space in a web-like structure. Originally described as an anti-microbial function, this process has been implicated in the pathogenesis of pancreatic disease. In addition, NETs are upregulated during physiologic wound-healing and coagulation.

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Article Synopsis
  • Different aspects of biodiversity, like the number of species on islands, change at different rates because of human activity, and this isn't as simple as it seems.
  • Sometimes when humans impact biodiversity, it can either make ecosystems stronger against extinction or cause a lot of species to disappear rapidly.
  • A study found that while islands might get more species from human help, the total number of species worldwide is going down, but those new communities can still be strong and work well together.
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