Publications by authors named "B M Cannon"
Until two decades ago, brown adipose tissue (BAT) was studied primarily as a thermogenic organ of small rodents in the context of cold adaptation. The discovery of functional human BAT has opened new opportunities to understand its physiological role in energy balance and therapeutic applications for metabolic disorders. Significantly, the role of BAT extends far beyond thermogenesis, including glucose and lipid homeostasis, by releasing mediators that communicate with other cells and organs.
View Article and Find Full Text PDFWe present a scalar, time-dependent, plane-wave model for stimulated Brillouin scattering (SBS) within a fiber amplifier having a seed linewidth comparable to, or greater than, the Brillouin frequency shift. The broadband model introduces the existence of a backward anti-Stokes wave, in addition to the Stokes wave present in the narrowband model. The model also incorporates a Fresnel reflection within the fiber or at the exit face.
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- Cardiac pressure overload can lead to problems for patients with congenital heart defects, and using stem cell-derived heart cells might help improve heart function alongside surgery.
- Researchers successfully implanted human stem cell-derived heart cells into the hearts of rhesus macaques facing induced pressure overload, achieving good integration with the existing heart tissue.
- Although some monkeys experienced episodes of ventricular tachycardia after the cell transplant, these events generally resolved within a few weeks, indicating a need for monitoring but also promising potential for this treatment approach.
Recent patch-clamp studies of mitoplasts have challenged the traditional view that classical chemical uncoupling (by e.g. FCCP or DNP) is due to the protonophoric property of these substances themselves.
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