Sensitized corticosterone responses do not mediate the enhanced fear memories in chronically stressed rats.

Following a stressful event, the hypothalamus-pituitary-adrenal axis mediates the release of the stress hormone cortisol (corticosterone in rodents; CORT). Elevated CORT binds to glucocorticoid receptors to mediate physiological responses including facilitating memory formation. Previous work from our laboratory demonstrated that male rats exposed to chronic stress demonstrate enhanced contextual fear memories and sensitized CORT responses to subsequent stress exposure; however, this is unknown in female rats.

Pheochromocytoma and von Hippel-Lindau's disease.

Two families with von Hippel-Lindau's disease with associated pheochromocytoma are presented. We include a review of the literature on this association, and discuss its significance for the ophthalmologist.

Neovascular glaucoma in a university clinic.

A comparative survey of 100 consecutive clinic and private glaucoma patients was made in an attempt to determine the nature of these populations. Secondary glaucoma was found four times more frequently in the clinic group. The most common secondary form was neovascular glaucoma.