Correction to: Genotyping of human cyst in Morocco.

[This corrects the article DOI: 10.1007/s12639-019-01127-1.].

Estimated Incidence and Prevalence of Serious Fungal Infections in Morocco.

Few data are published from Morocco on fungal disease, although numerous case reports attest to a wide range of conditions in the country. Here, we estimate for the first time the incidence and prevalence of serious fungal diseases in the country. Detailed literature searches in English and French were conducted for all serious fungal infections.

Multiple pelvic and thigh hydatid cyst: a case report.

Bone cystic echinococcosis is rare disease and its management remain difficult to treat due to frequent recurrences, related to certain locations such as proximal femur and ilium, where radical surgery is difficult to achieve. Medical therapy using Mebendazol can be an ultimate way to insure stabilization and remission of the parasitosis. We present a case of a 37-year-old male who had complaints of pain in left hip and limp four years after surgical management of pertrochanteric fracture of his right lower limb.

Targeting the GRP78-Dependant SARS-CoV-2 Cell Entry by Peptides and Small Molecules.

The global burden of infections and the rapid spread of viral diseases show the need for new approaches in the prevention and development of effective therapies. To this end, we aimed to explore novel inhibitor compounds that can stop replication or decrease the viral load of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for which there is currently no approved treatment. Besides using the angiotensin-converting enzyme (ACE2) receptor as a main gate, the CoV-2 can bind to the glucose-regulating protein 78 (GRP78) receptor to get into the cells to start an infection.

In silico exploration of small-molecule α-helix mimetics as inhibitors of SARS-COV-2 attachment to ACE2.

The novel coronavirus, SARS-CoV-2, has infected more than 10 million people and caused more than 502,539 deaths worldwide as of June 2020. The explosive spread of the virus and the rapid increase in the number of cases require the immediate development of effective therapies and vaccines as well as accurate diagnosis tools. The pathogenesis of the disease is triggered by the entry of SARS-CoV-2 via its spike protein into ACE2-bearing host cells, particularly pneumocytes, resulting in overactivation of the immune system, which attacks the infected cells and damages the lung tissue.