Publications by authors named "B Lin-Ju Yen"
Objective: To determine the feasibility of integrating Medicare Advantage (MA) admissions into the Centers for Medicare & Medicaid Services (CMS) hospital outcome measures through combining Medicare Advantage Organization (MAO) encounter- and hospital-submitted inpatient claims.
Data Sources And Study Setting: Beneficiary enrollment data and inpatient claims from the Integrated Data Repository for 2018 Medicare discharges.
Study Design: We examined timeliness of MA claims, compared diagnosis and procedure codes for admissions with claims submitted both by the hospital and the MAO (overlapping claims), and compared demographic characteristics and principal diagnosis codes for admissions with overlapping claims versus admissions with a single claim.
Article Synopsis
- The study investigates how excessive consumption of simple sugars negatively affects bone health, particularly during adolescence and early adulthood, which is critical for preventing osteoporosis later in life.
- Researchers performed bioinformatics analyses and conducted experiments on mesenchymal stromal cells (MSCs) to understand the mechanisms behind this link, focusing on mitochondrial function and differentiation into bone-forming cells.
- Findings show that high glucose conditions harm MSC function by depleting a key coenzyme (NAD), leading to a decrease in bone formation and an increase in fat cell formation; however, supplementing with NAD can quickly reverse these effects.
Purpose: Alström Syndrome (AS) is a rare autosomal recessive monogenic ciliopathy which is caused by a mutation of the Alström syndrome 1 (ALMS1) gene. It is a multisystemic disorder characterized by insulin resistance, childhood obesity, cardiomyopathy, progressive hepatic and renal failure, sensorineural hearing loss and retinal degeneration. Herein, we aimed to report a novel variant in ALMS1 gene causing AS in a patient presenting with visual impairment.
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