HLA Awareness in tissue decellularization: A paradigm shift for enhanced biocompatibility, studied on the model of the human fascia lata graft.

Last twenties, tissue engineering has rapidly advanced to address the shortage of organ donors. Decellularization techniques have been developed to mitigate immune rejection and alloresponse in transplantation. However, a clear definition of effective decellularization remains elusive.

Enhancing the biological integration of massive bone allografts: A porcine preclinical in vivo pilot-study.

Critical bone loss can have several origins: infections, tumors or trauma. Therefore, massive bone allograft can be a solution for limb salvage. Such a biological reconstruction should have the ideal biomechanical qualities.

A single Angiofil-latex injection for both radiological and anatomical assessment of arterial territories in the limbs.

Introduction: Postmortem evaluation of the human vascular system has a long history, with advancements ranging from dissections to modern imaging techniques like computed tomography (CT scan). This study designs a novel combination of Angiofil, a liquid radiopaque polymer, and latex, a flexible cast material, for cadaveric vascular analysis.

Material & Methods: The aim was to synergize the advantages of both components, providing accurate radiological images and optimal dissection conditions.

Impact of NaOH based perfusion-decellularization protocol on mechanical resistance of structural bone allografts.

Introduction: To mitigate the post-operative complication rates associated with massive bone allografts, tissue engineering techniques have been employed to decellularize entire bones through perfusion with a sequence of solvents. Mechanical assessment was performed in order to compare conventional massive bone allografts and perfusion/decellularized massive bone allografts.

Material And Methods: Ten porcine femurs were included.