Identifying high-impact-opportunity hospitals for improving healthcare quality based on a national population analysis of inter-hospital variation in mortality, readmissions and prolonged length of stay.

Objectives: To study between-hospital variation in mortality, readmissions and prolonged length of stay across Belgian hospitals.

Design: A retrospective nationwide observational study.

Setting: Secondary and tertiary acute-care hospitals in Belgium.

Earth Observation Data to Support Environmental Justice: Linking Non-Permitted Poultry Operations to Social Vulnerability Indices.

Concentrated Animal Feeding Operations (CAFOs) apply massive amounts of untreated waste to nearby farmlands, with severe environmental health impacts of swine CAFOs and proximity to disadvantaged communities well documented in some US regions. Most studies documenting the impacts of CAFOs rely almost exclusively on CAFO locations known from incomplete public records. Poultry CAFOs generate dry waste and operate without federal permits; thus, their environmental justice (EJ) impacts are undocumented.

Pressure-Enabled Drug Delivery Significantly Increases Intra-Arterial Delivery of Embolic Microspheres to Liver Tumors in a Porcine Model.

This study aimed to test the hypothesis that pressure-enabled drug delivery (PEDD) with a pressure-modulating microcatheter device (TriNav; TriSalus Life Sciences, Westminster, Colorado) would increase delivery of microspheres via hepatic arterial infusion to liver tumors in an Oncopig model (Sus Clinicals, Chicago, Illinois) when compared with a conventional end-hole microcatheter. Trisacryl gelatin microspheres (100-300 μm in size) were fluorescently labeled and infused into porcine liver tumors using conventional technique (n = 8) or by PEDD (n = 8). Liver tissue was harvested, and images were analyzed with a custom deep learning algorithm (Visiopharm, Hørsholm, Denmark) to quantitate signal intensity.