Publications by authors named "B Launer"

Article Synopsis
  • The study aimed to evaluate how well ChatGPT can interpret medical imaging in urology, focusing on its strengths and weaknesses as a diagnostic tool in healthcare.
  • Using cases from Radiopaedia.com, ChatGPT analyzed CT and MRI images to provide ranked differential diagnoses, assessing its accuracy with and without organ-specific guidance.
  • Results showed that while ChatGPT had low initial accuracy in diagnosing conditions, it improved significantly with organ guidance, indicating that the AI can enhance medical imaging diagnostics when given clear direction and more data.
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Article Synopsis
  • Researchers created AI-based histologic assays to predict the likelihood of recurrence and progression in patients with high-risk non-muscle invasive bladder cancer after treatment with intravesical BCG.
  • They analyzed whole-slide images from bladder tumor resections and clinical data from multiple centers, successfully categorizing cases into high or low risk for various outcomes.
  • The validation cohort showed that high-risk patients had significantly worse survival outcomes, indicating that these AI assays provide crucial predictive information beyond traditional clinical factors.
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Prostate cancer (PCa) screening has evolved beyond PSA and digital rectal exam to include multiparametric prostate MRI (mpMRI). Incorporating this advanced imaging tool has further limited the well-established problem of overdiagnosis, aiding in the identification of higher grade, clinically significant cancers. For this reason, mpMRI has become an important part of the diagnostic pathway and is recommended across guidelines in biopsy naïve patients or for patients with prior negative biopsy.

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Bone and joint infections (BJIs) are common infections increasingly managed with oral therapy. However, there are limited safe oral options for many Gram-positive pathogens. In animal studies and short-term human use, tedizolid lacks the hematologic and neurologic toxicity of the other available oxazolidinone, linezolid.

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