Publications by authors named "B Lamprecht"
Article Synopsis
- Researchers examined the effectiveness of transmission electron microscopy (TEM) on lung samples from 16 patients with fibrotic interstitial lung disease (ILD) using transbronchial lung cryobiopsy (TBLC) techniques.
- The TEM analysis revealed high-quality images with minimal artifacts, highlighting significant endothelial abnormalities in ILD patients, such as protrusions and surface defects.
- These microvascular changes were more common in younger patients and those with specific ILD characteristics, suggesting that TEM could be a useful tool for further understanding lung disease pathology.
Article Synopsis
- * A simulation targeted a high-risk population (ages 50-74 with a smoking history), revealing that a 50% participation rate could result in 56,122 quality-adjusted life years (QALYs) and 84,049 life years gained, with an incremental cost-effectiveness ratio (ICER) of EUR 24,627 per QALY.
- * The LCS program would lead to early detection of 25,893 lung cancers and prevent 11,906 premature deaths,
Background: The clinical spectrum of fibrotic interstitial lung diseases (ILDs) is highly heterogeneous. We aimed to evaluate the prognostic value of widely available baseline biomarkers for the improvement of lung function in patients with fibrotic ILDs.
Methods: This registry-based study included 142 patients with fibrotic ILDs as defined by the presence of reticulation, traction bronchiectasis or honeycombing on initial high-resolution computed tomography (HRCT).
BACKGROUND A 52-year-old male patient presented with symptoms of chronic cough and persistent tracheal irritation 26 years after surgical closure of a tracheostoma, supported by an autologous auricular cartilage graft and cutaneous transplant. At the initial clinical presentation, the patient was an active smoker, with a cumulative dose of 31 pack years. CASE REPORT Bronchoscopy revealed endotracheal hair growth and local inflammation at the graft site.
View Article and Find Full Text PDFBackground: Reference values for lung volumes are necessary to identify and diagnose restrictive lung diseases and hyperinflation, but the values have to be validated in the relevant population. Our aim was to investigate the Global Lung Function Initiative (GLI) reference equations in a representative healthy Austrian population and create population-derived reference equations if poor fit was observed.
Methods: We analysed spirometry and body plethysmography data from 5371 respiratory healthy subjects (6-80 years) from the Austrian LEAD Study.