Importance of Fecal Microbiota Transplantation and Molecular Regulation as Therapeutic Strategies in Inflammatory Bowel Diseases.

Noncoding RNAs, particularly microRNAs (miRNAs) and small interfering RNAs (siRNAs), have emerged as key players in the pathogenesis and therapeutic strategies for inflammatory bowel disease (IBD). MiRNAs, small endogenous RNA molecules that silence target mRNAs to regulate gene expression, are closely linked to immune responses and inflammatory pathways in IBD. Notably, miR-21, miR-146a, and miR-155 are consistently upregulated in IBD, influencing immune cell modulation, cytokine production, and the intestinal epithelial barrier.

Rejuvenating multiple true-false: proposing fairer scoring methods.

Introduction: The COVID-19 pandemic has reached a phase where many have been infected at least once. Healthcare workers were not spared from being infected. This study aimed to determine the period prevalence of COVID-19 among the paediatric healthcare workers in Negeri Sembilan as the country transitioned into an endemic phase of the pandemic.

Accuracy of Sexual and Reproductive Health Information among Adolescent Girls: A Cross-Sectional Study.

Background: The leading cause of death for girls aged 15-19 years globally is complications from pregnancy and childbirth. Girls have poor access to sexual and reproductive health (SRH) services, including information.

Study Objective: To describe the accuracy of SRH information (SRHI) and its associated factors among adolescent girls in Uganda METHODS: We conducted a cross-sectional study among girls aged 13-19 years in an urban district and a rural district.

Transmission route and introduction of pandemic SARS-CoV-2 between China, Italy, and Spain.

We present a phylodynamic and phylogeographic analysis of this new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in this report. A tree of maximum credibility was constructed using the 72 entire genome sequences of this virus, from the three countries (China, Italy, and Spain) available as of 26 March 2020 on the GISAID reference frame. To schematize the current SARS-CoV-2 migration scenario between and within the three countries chosen, using the multitype bearth-death model implemented in BEAST2.