Publications by authors named "B L Roper"
Background: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a recently emerged tickborne virus in east Asia with over 18,000 confirmed cases. With a high case fatality ratio, SFTSV has been designated a high priority pathogen by the WHO and the NIAID. Despite this, there are currently no approved therapies or vaccines to treat or prevent SFTS.
View Article and Find Full Text PDFthe parasite responsible for nearly all cases of severe malaria, must survive challenging environments to persist in its human host. Symptomatic malaria is characterized by periodic fevers corresponding to the 48-hour asexual reproduction of in red blood cells. As a result, has evolved a diverse collection of heat shock proteins to mitigate the stresses induced by temperature shifts.
View Article and Find Full Text PDFBackground: Performance validity (PV) and symptom validity (SV) tests assess biased responding that impact scores on neuropsychological tests. The extent to which PV and SV represent overlapping or unique constructs remains incompletely defined, especially among psychiatric patients in a non-forensic setting. The current study investigated this question using confirmatory factor analysis.
View Article and Find Full Text PDFArticle Synopsis
- * The study produced various mRNAs using different engineered T7 RNA polymerases to analyze key properties like integrity and functional activity, particularly focusing on impurities that could affect therapeutic efficacy.
- * Findings emphasize the need for sophisticated analytical methods to better characterize mRNA impurities and their effects on cellular responses, which is crucial for ensuring the safety and effectiveness of RNA-based treatments.
Introduction: Pediatric pelvic and acetabular fractures are rare but potentially devastating injuries and significant management variation exists across the United States. This study sought to elucidate treatment decision-making trends, involvement of adult trauma fellowship-trained surgeons in pediatric care, and pre- and postoperative transfer patterns.
Methods: Pediatric orthopaedic surgeons who serve as trauma liaisons at 20 PTCs were surveyed regarding training, practice volume, and factors contributing to institutional management of pelvic and acetabular injuries.