Publications by authors named "B L Ribeiro"

Lutzomyia longipalpis Lutz & Neiva, 1912 (Diptera, Psychodidae), is the primary vector of Leishmania infantum Nicole, 1908, the etiological agent of American visceral leishmaniasis. During their development, sandfly larvae pass through four instars, consuming soil particles enriched with microorganisms and decomposing organic material. In numerous insect species, the intestinal epithelium not only secretes digestive enzymes and absorbs digested nutrients but also carries out additional functions, such as regulating luminal pH and facilitating the absorption or secretion of ions and water.

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Ethnopharmacological Relevance: Anxiety and depression are leading causes of disability worldwide, often exacerbated by chronic stress. Schinus terebinthifolia Raddi. has been used in traditional medicine for several purposes.

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Macrophages represent a fundamental component of the innate immune system that play a critical role in detecting and responding to pathogens as well as danger signals. Leishmania spp. infections lead to a notable alteration in macrophage metabolism, whereby infected cells display heightened energy metabolism that is linked to the integrity of host mitochondria.

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Article Synopsis
  • Long COVID, also known as post-acute sequelae of COVID-19 (PASC), involves lasting symptoms affecting various body systems, particularly the central nervous system (CNS) which includes issues like fatigue, brain fog, and cognitive deficits.
  • The review highlights potential mechanisms for neuro-PASC, suggesting that vascular dysfunction and disruption of the blood-brain barrier (BBB) could be key contributors to these neurological symptoms.
  • It further investigates the role of the COVID-19 spike protein interacting with brain cell receptors, which may play a significant part in the pathophysiology of long COVID symptoms.
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Background: Recent evidence indicates that statins have anti-inflammatory and antioxidant effects, leading to several investigations of whether statins have a neuroprotective effect and may benefit patients with Parkinson's disease (PD). However, the potential mechanisms of this class of medications as modifiers of the course of PD in already diagnosed patients is still unclear.

Objectives: To assess the effectiveness of statins as modifiers of established PD.

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