[Microcirculation in patients with chronic gastritis depending on its exacerbation severity and morphological type].

The study of microvasculature in bioptic specimens of gastric mucosa and of conjunctival microcirculation from 254 patients with chronic gastritis revealed that exacerbation of the disease proceeds with severe disorders of terminal blood flow which are typical for the chronic relapse trombohemorrhagic syndrome and have generalized character. The microvascular disorders is manifested by plasma- and hemorrhages, by microvascular spasm and dilatation, intravascular hemostasis and microthrombosis. These manifestations were more expressed over the period of bright marked exacerbation of the disease and in patients with erosive affection of gastric mucosa.

[Variants in the course of chronic alcoholic gastritis].

Functional and structural changes in the stomach, vegetative tone, microcirculation, histamine metabolism were studied in 136 male alcoholics. The results allowed the authors to distinguish clinico-pathogenetic variants of chronic alcoholic gastritis which can be used for objective evaluation of the disease severity and serve basis for design of adequate therapy at different stages of the disease progression.

[Chronic gastritis from the aspect of a thrombohemorrhagic syndrome].

As many as 148 patients were examined to demonstrate that chronic gastritis (CG) runs its course in the presence of marked changes in microcirculation and hemostasis which go into the framework of the chronic recurrent thrombohemorrhagic syndrome. The manifestations of the latter one were more appreciable in a dramatic exacerbation of the disease, erosive gastritis, diffuse atrophy of the mucous membrane and secretory insufficiency of the stomach, and disease standing over 10 years. The disorders indicated are involved into the pathogenesis of CG and promote the development of morphofunctional alterations in the gastric mucosa.