Publications by authors named "B L Jaber"

Article Synopsis
  • Recent research has classified a specific bacterial strain as low-risk for producing a certain enzyme affecting antibiotic efficacy, but there is limited data on how antibiotic choices impact patient outcomes in bacteremia.
  • This study focused on comparing clinical outcomes between patients treated with AmpC-directed β-lactam therapy and narrower spectrum therapies for ceftriaxone-susceptible bacteremia, reviewing records over an 8-year period from seven hospitals.
  • Results indicated that while carbapenem therapy showed trends toward lower mortality and longer treatment duration, these differences weren't statistically significant, emphasizing the need for proper antibiotic stewardship to avoid the development of drug-resistant bacteria.
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Objective: To examine the rate of abidance and adherence to voice therapy (VT) in a group of Lebanese patients with voice disorders, and to analyze the correlation between the rate of abidance, adherence, and socioeconomic factors in addition to patient- and disease-related factors.

Study Design: Retrospective chart review.

Methods: The medical records of patients with voice disorders who presented to the voice unit in a tertiary referral center between January 2022 and December 2023 were reviewed.

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To explore the risk of obstructive sleep apnea (OSA) in patients with primary muscle tension dysphonia (MTD). The medical records of patients diagnosed with primary MTD between November 2021 and March 2023, were reviewed. The risk of having OSA was assessed by looking at the scores of two validated questionnaires, namely the STOP-BANG questionnaire and the Berlin questionnaire.

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Background: Propofol, a commonly used agent for short- and long-term sedation, is associated with acute pancreatitis. The main indirect mechanism of propofol-associated acute pancreatitis is by inducing hypertriglyceridemia. Patients with severe coronavirus disease 2019 (COVID-19) pneumonia often require prolonged mechanical ventilation and sedation.

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Risdiplam is a once-daily oral, survival of motor neuron 2 (SMN2) splicing modifier approved for the treatment of spinal muscular atrophy (SMA). JEWELFISH (NCT03032172) investigated the safety, tolerability, pharmacokinetics (PK), and PK/pharmacodynamic (PD) relationship of risdiplam in non-treatment-naïve patients with SMA. JEWELFISH enrolled adult and pediatric patients (N = 174) with confirmed diagnosis of 5q-autosomal recessive SMA who had previously received treatment with nusinersen (n = 76), onasemnogene abeparvovec (n = 14), olesoxime (n = 71), or were enrolled in the MOONFISH study (NCT02240355) of the splicing modifier RG7800 (n = 13).

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