Publications by authors named "B L Everett"
Importance: Evidence on cardiovascular benefits and safety of sodium-glucose cotransporter 2 (SGLT-2) inhibitors is mainly from placebo-controlled trials. Therefore, the comparative effectiveness and safety of individual SGLT-2 inhibitors remain unknown.
Objective: To compare the use of canagliflozin or dapagliflozin with empagliflozin for a composite outcome (myocardial infarction [MI] or stroke), heart failure hospitalization, MI, stroke, all-cause death, and safety outcomes, including diabetic ketoacidosis (DKA), lower-limb amputation, bone fracture, severe urinary tract infection (UTI), and genital infection and whether effects differed by dosage or cardiovascular disease (CVD) history.
Secreted nucleases reclaim extracellular DNA during biofilm development.
NPJ Biofilms Microbiomes
October 2024
DNA is the genetic code found inside all living cells and its molecular stability can also be utilized outside the cell. While extracellular DNA (eDNA) has been identified as a structural polymer in bacterial biofilms, whether it persists stably throughout development remains unclear. Here, we report that eDNA is temporarily invested in the biofilm matrix before being reclaimed later in development.
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- The study aimed to assess if there are differences in negative neonatal outcomes (like preterm birth and low birth weight) for babies born to LGB+ parents compared to completely heterosexual parents.
- Researchers analyzed long-term data from the Nurses' Health Study II, focusing on mothers who reported their sexual orientation and live births from 2001 and 2009, totaling 70,642 participants.
- Findings indicated that all LGB+ groups had a higher risk of preterm births and low birth weight compared to heterosexual parents, particularly those who identified as heterosexual but had past same-sex attractions; however, the risk was not statistically significant for lesbian or gay and bisexual participants.