Publications by authors named "B L Bassler"

Breastmilk is known to provide optimal nutrition for infant growth and development. A cross-sectional analysis of nationally representative US data from 2016 to 2021 revealed that >90% of lactating mothers reported using breast pumps to express milk. We conducted a survey of = 1,049 lactating or recently lactating individuals from a US nationally representative population to explore breastmilk storage practices among this group.

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Quorum sensing (QS) is a cell-to-cell communication process that enables bacteria to coordinate group behaviors. In colonies, a program of spatial-temporal cell death is among the QS-controlled traits. Cell death occurs in two phases, first along the colony rim, and subsequently, at the colony center.

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Article Synopsis
  • * The study reveals that the master QS regulator, HapR, does not control the cell death mechanism directed by the type VI secretion system (T6SS) but instead activates a separate operon of four unknown genes that drive cell death in colonies.
  • * This discovery indicates that bacteria possess an alternative pathway for cell death independent of T6SS, enhancing our understanding of bacterial cell death mechanisms and their role in community structure.
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Quorum sensing (QS) is a process of cell-to-cell communication that bacteria use to synchronize collective behaviors. QS relies on the production, release, and group-wide detection of extracellular signaling molecules called autoinducers. Vibrios use two QS systems: the LuxO-OpaR circuit and the VqmA-VqmR circuit.

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Bacteria commonly exist in multicellular, surface-attached communities called biofilms. Biofilms are central to ecology, medicine, and industry. The pathogen forms biofilms from single founder cells that, via cell division, mature into three-dimensional structures with distinct, yet reproducible, regional architectures.

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